2024

Hybrid Neural State-Space Modeling for Supervised and Unsupervised Electrocardiographic Imaging.
Jiang X, Missel R, Toloubidokhti M, Gillette K, Prassl AJ, Plank G, Milan Horacek B, Sapp JL, Wang L (2024) IEEE Trans Med Imaging, PPPMID: 38478452, DOI: 10.1109/TMI.2024.3377094

Developing Cardiac Digital Twins at Scale: Insights from Personalised Myocardial Conduction Velocity.
Qian S, Ugurlu D, Fairweather E, Strocchi M, Toso LD, Deng Y, Plank G, Vigmond E, Razavi R, Young A, Lamata P, Bishop M, Niederer S (2024) medRxiv, In Press.
PMID: 38106072, DOI: 10.1101/2023.12.05.23299435

A Semi-automatic Pipeline for Generation of Large Cohorts of Four-Chamber Heart Meshes.
Strocchi M, Rodero C, Roney CH, Mendonca Costa C, Plank G, Lamata P, Niederer SA (2024) Methods Mol Biol, 2735: 117-127.
PMID: 38038846, DOI: 10.1007/978-1-0716-3527-8_7

2023

Neural network emulation of the human ventricular cardiomyocyte action potential: a tool for more efficient computation in pharmacological studies.
Grandits T, Augustin CM, Haase G, Jost N, Mirams GR, Niederer SA, Plank G, Varró A, Virág L, Jung A (2023) bioRxiv, In Press.
PMID: 38234850, DOI: 10.1101/2023.08.16.553497

Constructing bilayer and volumetric atrial models at scale.
Roney CH, Solis Lemus JA, Lopez Barrera C, Zolotarev A, Ulgen O, Kerfoot E, Bevis L, Misghina S, Vidal Horrach C, Jaffery OA, Ehnesh M, Rodero C, Dharmaprani D, Ríos-Muñoz GR, Ganesan A, Good WW, Neic A, Plank G, Hopman LHGA, Götte MJW, Honarbakhsh S, Narayan SM, Vigmond E, Niederer S (2023) Interface Focus, 13(6): 20230038.
PMID: 38106921, DOI: 10.1098/rsfs.2023.0038

Sterol interactions influence the function of Wsc sensors.
Bernauer L, Berzak P, Lehmayer L, Messenlehner J, Oberdorfer G, Zellnig G, Wolinski H, Augustin C, Baeck M, Emmerstorfer-Augustin A (2023) J Lipid Res, 64(12): 100466.
PMID: 37918524, DOI: 10.1016/j.jlr.2023.100466

Guided implantation of a leadless left ventricular endocardial electrode and acoustic transmitter using computed tomography anatomy, dynamic perfusion and mechanics, and predicted activation pattern.
Sidhu BS, Lee AWC, Gould J, Porter B, Sieniewicz B, Elliott MK, Mehta VS, Wijesuriya N, Amadou AA, Plank G, Haberland U, Rajani R, Rinaldi CA, Niederer SA (2023) Heart Rhythm, 20(11): 1481-1488.
PMID: 37453603, DOI: 10.1016/j.hrthm.2023.07.007

MedalCare-XL: 16,900 healthy and pathological synthetic 12 lead ECGs from electrophysiological simulations.
Gillette K, Gsell MAF, Nagel C, Bender J, Winkler B, Williams SE, Bär M, Schäffter T, Dössel O, Plank G, Loewe A (2023) Sci Data, 10(1): 531.
PMID: 37553349, DOI: 10.1038/s41597-023-02416-4

Arrhythmogenic vulnerability of re-entrant pathways in post-infarct ventricular tachycardia assessed by advanced computational modelling.
Bhagirath P, Campos FO, Postema P, Kemme MJB, Wilde AAM, Prassl AJ, Neic A, Rinaldi CA, Götte MJW, Plank G, Bishop MJ (2023) Europace, 25(9)PMID: 37421339, DOI: 10.1093/europace/euad198

Frequency Domain Analysis of Endocardial Electrograms for Detection of Nontransmural Myocardial Fibrosis in Nonischemic Cardiomyopathy.
Whitaker J, Baum TE, Qian P, Prassl AJ, Plank G, Blankstein R, Cochet H, Sauer WH, Bishop MJ, Tedrow U (2023) JACC Clin Electrophysiol, 9(7 Pt 1): 923-935.
PMID: 36669900, DOI: 10.1016/j.jacep.2022.11.019

Cell to whole organ global sensitivity analysis on a four-chamber heart electromechanics model using Gaussian processes emulators.
Strocchi M, Longobardi S, Augustin CM, Gsell MAF, Petras A, Rinaldi CA, Vigmond EJ, Plank G, Oates CJ, Wilkinson RD, Niederer SA (2023) PLoS Comput Biol, 19(6): e1011257.
PMID: 37363928, DOI: 10.1371/journal.pcbi.1011257

Mechanoelectric effects in healthy cardiac function and under Left Bundle Branch Block pathology.
Petras A, Gsell MAF, Augustin CM, Rodriguez-Padilla J, Jung A, Strocchi M, Prinzen FW, Niederer SA, Plank G, Vigmond EJ (2023) Comput Biol Med, 156: 106696.
PMID: 36870172, DOI: 10.1016/j.compbiomed.2023.106696

Effect of scar and His-Purkinje and myocardium conduction on response to conduction system pacing.
Strocchi M, Gillette K, Neic A, Elliott MK, Wijesuriya N, Mehta V, Vigmond EJ, Plank G, Rinaldi CA, Niederer SA (2023) J Cardiovasc Electrophysiol, 34(4): 984-993.
PMID: 36738149, DOI: 10.1111/jce.15847

Assessing the arrhythmogenic risk of engineered heart tissue patches through in silico application on infarcted ventricle models.
Fassina D, M Costa C, Bishop M, Plank G, Whitaker J, Harding SE, Niederer SA (2023) Comput Biol Med, 154: 106550.
PMID: 36701966, DOI: 10.1016/j.compbiomed.2023.106550

Non-invasive localization of post-infarct ventricular tachycardia exit sites to guide ablation planning: a computational deep learning platform utilizing the 12-lead electrocardiogram and intracardiac electrograms from implanted devices.
Monaci S, Qian S, Gillette K, Puyol-Antón E, Mukherjee R, Elliott MK, Whitaker J, Rajani R, O'Neill M, Rinaldi CA, Plank G, King AP, Bishop MJ (2023) Europace, 25(2): 469-477.
PMID: 36369980, DOI: 10.1093/europace/euac178

Subthreshold delayed afterdepolarizations provide an important arrhythmogenic substrate in the border zone of infarcted hearts.
Campos FO, Shiferaw Y, Whitaker J, Plank G, Bishop MJ (2023) Heart Rhythm, 20(2): 299-306.
PMID: 36343889, DOI: 10.1016/j.hrthm.2022.10.026

Treatment Planning for Atrial Fibrillation Using Patient-Specific Models Showing the Importance of Fibrillatory-Areas.
Kamali R, Gillette K, Tate J, Abhyankar DA, Dosdall DJ, Plank G, Bunch TJ, Macleod RS, Ranjan R (2023) Ann Biomed Eng, 51(2): 329-342.
PMID: 35930093, DOI: 10.1007/s10439-022-03029-5

Comparison of Propagation Models and Forward Calculation Methods on Cellular, Tissue and Organ Scale Atrial Electrophysiology.
Nagel C, Espinosa CB, Gillette K, Gsell MAF, Sanchez J, Plank G, Dossel O, Loewe A (2023) IEEE Trans Biomed Eng, 70(2): 511-522.
PMID: 35921339, DOI: 10.1109/TBME.2022.3196144

Calibration of Cohorts of Virtual Patient Heart Models Using Bayesian History Matching.
Rodero C, Longobardi S, Augustin C, Strocchi M, Plank G, Lamata P, Niederer SA (2023) Ann Biomed Eng, 51(1): 241-252.
PMID: 36271218, DOI: 10.1007/s10439-022-03095-9

2022

Leadless biventricular left bundle and endocardial lateral wall pacing versus left bundle only pacing in left bundle branch block patients.
Strocchi M, Wijesuriya N, Elliott MK, Gillette K, Neic A, Mehta V, Vigmond EJ, Plank G, Rinaldi CA, Niederer SA (2022) Front Physiol, 13: 1049214.
PMID: 36589454, DOI: 10.3389/fphys.2022.1049214

Predicting arrhythmia recurrence following catheter ablation for ventricular tachycardia using late gadolinium enhancement magnetic resonance imaging: Implications of varying scar ranges.
Bhagirath P, Campos FO, Costa CM, Wilde AAM, Prassl AJ, Neic A, Plank G, Rinaldi CA, Götte MJW, Bishop MJ (2022) Heart Rhythm, 19(10): 1604-1610.
PMID: 35644355, DOI: 10.1016/j.hrthm.2022.05.021

Global Sensitivity Analysis of Four Chamber Heart Hemodynamics Using Surrogate Models.
Karabelas E, Longobardi S, Fuchsberger J, Razeghi O, Rodero C, Strocchi M, Rajani R, Haase G, Plank G, Niederer S (2022) IEEE Trans Biomed Eng, 69(10): 3216-3223.
PMID: 35353691, DOI: 10.1109/TBME.2022.3163428

A personalized real-time virtual model of whole heart electrophysiology.
Gillette K, Gsell MAF, Strocchi M, Grandits T, Neic A, Manninger M, Scherr D, Roney CH, Prassl AJ, Augustin CM, Vigmond EJ, Plank G (2022) Front Physiol, 13: 907190.
PMID: 36213235, DOI: 10.3389/fphys.2022.907190

Comparison between conduction system pacing and cardiac resynchronization therapy in right bundle branch block patients.
Strocchi M, Gillette K, Neic A, Elliott MK, Wijesuriya N, Mehta V, Vigmond EJ, Plank G, Rinaldi CA, Niederer SA (2022) Front Physiol, 13: 1011566.
PMID: 36213223, DOI: 10.3389/fphys.2022.1011566

An automated near-real time computational method for induction and treatment of scar-related ventricular tachycardias.
Campos FO, Neic A, Mendonca Costa C, Whitaker J, O'Neill M, Razavi R, Rinaldi CA, DanielScherr, Niederer SA, Plank G, Bishop MJ (2022) Med Image Anal, 80: 102483.
PMID: 35667328, DOI: 10.1016/j.media.2022.102483

Robust and efficient fixed-point algorithm for the inverse elastostatic problem to identify myocardial passive material parameters and the unloaded reference configuration.
Marx L, Niestrawska JA, Gsell MAF, Caforio F, Plank G, Augustin CM (2022) J Comput Phys, 463: 111266.
PMID: 35662800, DOI: 10.1016/j.jcp.2022.111266

Impact of intraventricular septal fiber orientation on cardiac electromechanical function.
Rodríguez-Padilla J, Petras A, Magat J, Bayer J, Bihan-Poudec Y, El Hamrani D, Ramlugun G, Neic A, Augustin CM, Vaillant F, Constantin M, Benoist D, Pourtau L, Dubes V, Rogier J, Labrousse L, Bernus O, Quesson B, Haïssaguerre M, Gsell M, Plank G, Ozenne V, Vigmond E (2022) Am J Physiol Heart Circ Physiol, 322(6): H936-H952.
PMID: 35302879, DOI: 10.1152/ajpheart.00050.2022

Correction: Linking statistical shape models and simulated function in the healthy adult human heart.
Rodero C, Strocchi M, Marciniak M, Longobardi S, Whitaker J, O'Neill MD, Gillette K, Augustin C, Plank G, Vigmond EJ, Lamata P, Niederer SA (2022) PLoS Comput Biol, 18(5): e1010196.
PMID: 35613091, DOI: 10.1371/journal.pcbi.1010196

An accurate, robust, and efficient finite element framework with applications to anisotropic, nearly and fully incompressible elasticity.
Karabelas E, Gsell MAF, Haase G, Plank G, Augustin CM (2022) Comput Methods Appl Mech Eng, 394: 114887.
PMID: 35432634, DOI: 10.1016/j.cma.2022.114887

Modelling the interaction between stem cells derived cardiomyocytes patches and host myocardium to aid non-arrhythmic engineered heart tissue design.
Fassina D, Costa CM, Longobardi S, Karabelas E, Plank G, Harding SE, Niederer SA (2022) PLoS Comput Biol, 18(4): e1010030.
PMID: 35363778, DOI: 10.1371/journal.pcbi.1010030

An Integrated Workflow for Building Digital Twins of Cardiac Electromechanics-A Multi-Fidelity Approach for Personalising Active Mechanics.
Jung A, Gsell MAF, Augustin CM, Plank G (2022) Mathematics (Basel), 10(5): 823.
PMID: 35295404, DOI: 10.3390/math10050823

Diversity and complexity of the cavotricuspid isthmus in rabbits: A novel scheme for classification and geometrical transformation of anatomical structures.
Arnold R, Hofer E, Haas J, Sanchez-Quintana D, Plank G (2022) PLoS One, 17(3): e0264625.
PMID: 35231058, DOI: 10.1371/journal.pone.0264625

Determining anatomical and electrophysiological detail requirements for computational ventricular models of porcine myocardial infarction.
Mendonca Costa C, Gemmell P, Elliott MK, Whitaker J, Campos FO, Strocchi M, Neic A, Gillette K, Vigmond E, Plank G, Razavi R, O'Neill M, Rinaldi CA, Bishop MJ (2022) Comput Biol Med, 141: 105061.
PMID: 34915331, DOI: 10.1016/j.compbiomed.2021.105061

A coupling strategy for a first 3D-1D model of the cardiovascular system to study the effects of pulse wave propagation on cardiac function.
Caforio F, Augustin CM, Alastruey J, Gsell MAF, Plank G (2022) Comput Mech, 70(4): 703-722.
PMID: 36124206, DOI: 10.1007/s00466-022-02206-6

Impact of anatomical reverse remodelling in the design of optimal quadripolar pacing leads: A computational study.
Rodero C, Strocchi M, Lee AWC, Rinaldi CA, Vigmond EJ, Plank G, Lamata P, Niederer SA (2022) Comput Biol Med, 140: 105073.
PMID: 34852973, DOI: 10.1016/j.compbiomed.2021.105073

2021

A computationally efficient physiologically comprehensive 3D-0D closed-loop model of the heart and circulation.
Augustin CM, Gsell MAF, Karabelas E, Willemen E, Prinzen FW, Lumens J, Vigmond EJ, Plank G (2021) Comput Methods Appl Mech Eng, 386: 114092.
PMID: 34630765, DOI: 10.1016/j.cma.2021.114092

Automated Framework for the Inclusion of a His-Purkinje System in Cardiac Digital Twins of Ventricular Electrophysiology.
Gillette K, Gsell MAF, Bouyssier J, Prassl AJ, Neic A, Vigmond EJ, Plank G (2021) Ann Biomed Eng, 49(12): 3143-3153.
PMID: 34431016, DOI: 10.1007/s10439-021-02825-9

Corrigendum to "Wind and fairness in ski jumping: A computer modelling analysis" [J. Biomech. 75 (2018) 147-153].
Jung A, Müller W, Staat M (2021) J Biomech, 128: 110690.
PMID: 34536903, DOI: 10.1016/j.jbiomech.2021.110690

Combining endocardial mapping and electrocardiographic imaging (ECGI) for improving PVC localization: A feasibility study.
Good WW, Zenger B, Bergquist JA, Rupp LC, Gillette K, Angel N, Chou D, Plank G, MacLeod RS (2021) J Electrocardiol, 69S: 51-54.
PMID: 34649726, DOI: 10.1016/j.jelectrocard.2021.08.013

Non-invasive simulated electrical and measured mechanical indices predict response to cardiac resynchronization therapy.
Lee AWC, Razeghi O, Solis-Lemus JA, Strocchi M, Sidhu B, Gould J, Behar JM, Elliott M, Mehta V, Plank G, Rinaldi CA, Niederer SA (2021) Comput Biol Med, 138: 104872.
PMID: 34598070, DOI: 10.1016/j.compbiomed.2021.104872

How Electrode Position Affects Selective His Bundle Capture: A Modelling Study.
Vigmond EJ, Neic A, Blauer J, Swenson D, Plank G (2021) IEEE Trans Biomed Eng, 68(11): 3410-3416.
PMID: 33835914, DOI: 10.1109/TBME.2021.3072334

Estimation and Validation of Cardiac Conduction Velocity and Wavefront Reconstruction Using Epicardial and Volumetric Data.
Good WW, Gillette KK, Zenger B, Bergquist JA, Rupp LC, Tate J, Anderson D, Gsell MAF, Plank G, MacLeod RS (2021) IEEE Trans Biomed Eng, 68(11): 3290-3300.
PMID: 33784613, DOI: 10.1109/TBME.2021.3069792

The Role of Myocardial Fiber Direction in Epicardial Activation Patterns via Uncertainty Quantification.
Rupp LC, Bergquist JA, Zenger B, Gillette K, Narayan A, Tate JD, Plank G, MacLeod RS (2021) Comput Cardiol (2010), 48PMID: 35449765, DOI: 10.23919/cinc53138.2021.9662950

The openCARP simulation environment for cardiac electrophysiology.
Plank G, Loewe A, Neic A, Augustin C, Huang YL, Gsell MAF, Karabelas E, Nothstein M, Prassl AJ, Sánchez J, Seemann G, Vigmond EJ (2021) Comput Methods Programs Biomed, 208: 106223.
PMID: 34171774, DOI: 10.1016/j.cmpb.2021.106223

A heuristic model-based approach for compensating wind effects in ski jumping.
Jung A, Müller W, Virmavirta M (2021) J Biomech, 125: 110585.
PMID: 34233216, DOI: 10.1016/j.jbiomech.2021.110585

GEASI: Geodesic-based earliest activation sites identification in cardiac models.
Grandits T, Effland A, Pock T, Krause R, Plank G, Pezzuto S (2021) Int J Numer Method Biomed Eng, 37(8): e3505.
PMID: 34170082, DOI: 10.1002/cnm.3505

Automated Localization of Focal Ventricular Tachycardia From Simulated Implanted Device Electrograms: A Combined Physics-AI Approach.
Monaci S, Gillette K, Puyol-Antón E, Rajani R, Plank G, King A, Bishop M (2021) Front Physiol, 12: 682446.
PMID: 34276403, DOI: 10.3389/fphys.2021.682446

A Framework for the generation of digital twins of cardiac electrophysiology from clinical 12-leads ECGs.
Gillette K, Gsell MAF, Prassl AJ, Karabelas E, Reiter U, Reiter G, Grandits T, Payer C, Štern D, Urschler M, Bayer JD, Augustin CM, Neic A, Pock T, Vigmond EJ, Plank G (2021) Med Image Anal, 71: 102080.
PMID: 33975097, DOI: 10.1016/j.media.2021.102080

Learning atrial fiber orientations and conductivity tensors from intracardiac maps using physics-informed neural networks.
Grandits T, Pezzuto S, Costabal FS, Perdikaris P, Pock T, Plank G, Krause R (2021) Funct Imaging Model Heart, 2021: 650-658.
PMID: 35098259, DOI: 10.1007/978-3-030-78710-3_62

Quantifying the spatiotemporal influence of acute myocardial ischemia on volumetric conduction velocity.
Good WW, Zenger B, Bergquist JA, Rupp LC, Gillette KK, Gsell MAF, Plank G, MacLeod RS (2021) J Electrocardiol, 66: 86-94.
PMID: 33836460, DOI: 10.1016/j.jelectrocard.2021.03.004

Linking statistical shape models and simulated function in the healthy adult human heart.
Rodero C, Strocchi M, Marciniak M, Longobardi S, Whitaker J, O'Neill MD, Gillette K, Augustin C, Plank G, Vigmond EJ, Lamata P, Niederer SA (2021) PLoS Comput Biol, 17(4): e1008851.
PMID: 33857152, DOI: 10.1371/journal.pcbi.1008851

Automatic reconstruction of the left atrium activation from sparse intracardiac contact recordings by inverse estimate of fibre structure and anisotropic conduction in a patient-specific model.
Lubrecht JM, Grandits T, Gharaviri A, Schotten U, Pock T, Plank G, Krause R, Auricchio A, Conte G, Pezzuto S (2021) Europace, 23(23 Suppl 1): i63-i70.
PMID: 33751078, DOI: 10.1093/europace/euaa392

Using machine learning to identify local cellular properties that support re-entrant activation in patient-specific models of atrial fibrillation.
Corrado C, Williams S, Roney C, Plank G, O'Neill M, Niederer S (2021) Europace, 23(23 Suppl 1): i12-i20.
PMID: 33437987, DOI: 10.1093/europace/euaa386

Assessing the ability of substrate mapping techniques to guide ventricular tachycardia ablation using computational modelling.
Campos FO, Orini M, Arnold R, Whitaker J, O'Neill M, Razavi R, Plank G, Hanson B, Porter B, Rinaldi CA, Gill J, Lambiase PD, Taggart P, Bishop MJ (2021) Comput Biol Med, 130: 104214.
PMID: 33476992, DOI: 10.1016/j.compbiomed.2021.104214

Late-Gadolinium Enhancement Interface Area and Electrophysiological Simulations Predict Arrhythmic Events in Patients With Nonischemic Dilated Cardiomyopathy.
Balaban G, Halliday BP, Porter B, Bai W, Nygåard S, Owen R, Hatipoglu S, Ferreira ND, Izgi C, Tayal U, Corden B, Ware J, Pennell DJ, Rueckert D, Plank G, Rinaldi CA, Prasad SK, Bishop MJ (2021) JACC Clin Electrophysiol, 7(2): 238-249.
PMID: 33602406, DOI: 10.1016/j.jacep.2020.08.036

Reconstructing vascular homeostasis by growth-based prestretch and optimal fiber deposition.
Wu J, Augustin CM, Shadden SC (2021) J Mech Behav Biomed Mater, 114: 104161.
PMID: 33229142, DOI: 10.1016/j.jmbbm.2020.104161

2020

His-bundle and left bundle pacing with optimized atrioventricular delay achieve superior electrical synchrony over endocardial and epicardial pacing in left bundle branch block patients.
Strocchi M, Lee AWC, Neic A, Bouyssier J, Gillette K, Plank G, Elliott MK, Gould J, Behar JM, Sidhu B, Mehta V, Bishop MJ, Vigmond EJ, Rinaldi CA, Niederer SA (2020) Heart Rhythm, 17(11): 1922-1929.
PMID: 32603781, DOI: 10.1016/j.hrthm.2020.06.028

3D Electrophysiological Modeling of Interstitial Fibrosis Networks and Their Role in Ventricular Arrhythmias in Non-Ischemic Cardiomyopathy.
Balaban G, Costa CM, Porter B, Halliday B, Rinaldi CA, Prasad S, Plank G, Ismail TF, Bishop MJ (2020) IEEE Trans Biomed Eng, 67(11): 3125-3133.
PMID: 32275581, DOI: 10.1109/TBME.2020.2976924

An Inverse Eikonal Method for Identifying Ventricular Activation Sequences from Epicardial Activation Maps.
Grandits T, Gillette K, Neic A, Bayer J, Vigmond E, Pock T, Plank G (2020) J Comput Phys, 419PMID: 32952215, DOI: 10.1016/j.jcp.2020.109700

Double-kissing culotte technique for coronary bifurcation stenting.
Toth GG, Sasi V, Franco D, Prassl AJ, Di Serafino L, Ng JCK, Szanto G, Schneller L, Ang HY, Plank G, Wijns W, Barbato E (2020) EuroIntervention, 16(9): e724-e733.
PMID: 32338608, DOI: 10.4244/EIJ-D-20-00130

In-silico pace-mapping using a detailed whole torso model and implanted electronic device electrograms for more efficient ablation planning.
Monaci S, Strocchi M, Rodero C, Gillette K, Whitaker J, Rajani R, Rinaldi CA, O'Neill M, Plank G, King A, Bishop MJ (2020) Comput Biol Med, 125: 104005.
PMID: 32971325, DOI: 10.1016/j.compbiomed.2020.104005

In silico Comparison of Left Atrial Ablation Techniques That Target the Anatomical, Structural, and Electrical Substrates of Atrial Fibrillation.
Roney CH, Beach ML, Mehta AM, Sim I, Corrado C, Bendikas R, Solis-Lemus JA, Razeghi O, Whitaker J, O'Neill L, Plank G, Vigmond E, Williams SE, O'Neill MD, Niederer SA (2020) Front Physiol, 11: 1145.
PMID: 33041850, DOI: 10.3389/fphys.2020.572874

Effect of Myocardial Fiber Direction on Epicardial Activation Patterns.
Rupp LC, Good WW, Bergquist JA, Zenger B, Gillette K, Plank G, MacLeod RS (2020) Comput Cardiol (2010), 47PMID: 33937432, DOI: 10.22489/cinc.2020.399

Quantifying the Spatiotemporal Influence of Acute Myocardial Ischemia on Volumetric Conduction Speeds.
Good WW, Zenger B, Bergquist JA, Rupp LC, Gillette K, Plank G, MacLeod RS (2020) Comput Cardiol (2010), 47PMID: 33937430, DOI: 10.22489/cinc.2020.279

Direct comparison of a novel antitachycardia pacing algorithm against present methods using virtual patient modeling.
Swenson DJ, Taepke RT, Blauer JJE, Kwan E, Ghafoori E, Plank G, Vigmond E, MacLeod RS, DeGroot P, Ranjan R (2020) Heart Rhythm, 17(9): 1602-1608.
PMID: 32438017, DOI: 10.1016/j.hrthm.2020.05.009

A computational investigation into rate-dependant vectorcardiogram changes due to specific fibrosis patterns in non-ischæmic dilated cardiomyopathy.
Gemmell PM, Gillette K, Balaban G, Rajani R, Vigmond EJ, Plank G, Bishop MJ (2020) Comput Biol Med, 123: 103895.
PMID: 32741753, DOI: 10.1016/j.compbiomed.2020.103895

Left ventricular endocardial pacing is less arrhythmogenic than conventional epicardial pacing when pacing in proximity to scar.
Mendonca Costa C, Neic A, Gillette K, Porter B, Gould J, Sidhu B, Chen Z, Elliott M, Mehta V, Plank G, Rinaldi CA, Bishop MJ, Niederer SA (2020) Heart Rhythm, 17(8): 1262-1270.
PMID: 32272230, DOI: 10.1016/j.hrthm.2020.03.021

A publicly available virtual cohort of four-chamber heart meshes for cardiac electro-mechanics simulations.
Strocchi M, Augustin CM, Gsell MAF, Karabelas E, Neic A, Gillette K, Razeghi O, Prassl AJ, Vigmond EJ, Behar JM, Gould J, Sidhu B, Rinaldi CA, Bishop MJ, Plank G, Niederer SA (2020) PLoS One, 15(6): e0235145.
PMID: 32589679, DOI: 10.1371/journal.pone.0235145

Personalization of electro-mechanical models of the pressure-overloaded left ventricle: fitting of Windkessel-type afterload models.
Marx L, Gsell MAF, Rund A, Caforio F, Prassl AJ, Toth-Gayor G, Kuehne T, Augustin CM, Plank G (2020) Philos Trans A Math Phys Eng Sci, 378(2173): 20190342.
PMID: 32448067, DOI: 10.1098/rsta.2019.0342

Creation and application of virtual patient cohorts of heart models.
Niederer SA, Aboelkassem Y, Cantwell CD, Corrado C, Coveney S, Cherry EM, Delhaas T, Fenton FH, Panfilov AV, Pathmanathan P, Plank G, Riabiz M, Roney CH, Dos Santos RW, Wang L (2020) Philos Trans A Math Phys Eng Sci, 378(2173): 20190558.
PMID: 32448064, DOI: 10.1098/rsta.2019.0558

The impact of wall thickness and curvature on wall stress in patient-specific electromechanical models of the left atrium.
Augustin CM, Fastl TE, Neic A, Bellini C, Whitaker J, Rajani R, O'Neill MD, Bishop MJ, Plank G, Niederer SA (2020) Biomech Model Mechanobiol, 19(3): 1015-1034.
PMID: 31802292, DOI: 10.1007/s10237-019-01268-5

Computational modeling of cardiac growth and remodeling in pressure overloaded hearts-Linking microstructure to organ phenotype.
Niestrawska JA, Augustin CM, Plank G (2020) Acta Biomater, 106: 34-53.
PMID: 32058078, DOI: 10.1016/j.actbio.2020.02.010

Simulating ventricular systolic motion in a four-chamber heart model with spatially varying robin boundary conditions to model the effect of the pericardium.
Strocchi M, Gsell MAF, Augustin CM, Razeghi O, Roney CH, Prassl AJ, Vigmond EJ, Behar JM, Gould JS, Rinaldi CA, Bishop MJ, Plank G, Niederer SA (2020) J Biomech, 101: 109645.
PMID: 32014305, DOI: 10.1016/j.jbiomech.2020.109645

Automating image-based mesh generation and manipulation tasks in cardiac modeling workflows using Meshtool.
Neic A, Gsell MAF, Karabelas E, Prassl AJ, Plank G (2020) SoftwareX, 11: 100454.
PMID: 32607406, DOI: 10.1016/j.softx.2020.100454

Versatile stabilized finite element formulations for nearly and fully incompressible solid mechanics.
Karabelas E, Haase G, Plank G, Augustin CM (2020) Comput Mech, 65(1): 193-215.
PMID: 31975744, DOI: 10.1007/s00466-019-01760-w

2019

Sex-Dependent QRS Guidelines for Cardiac Resynchronization Therapy Using Computer Model Predictions.
Lee AWC, O'Regan DP, Gould J, Sidhu B, Sieniewicz B, Plank G, Warriner DR, Lamata P, Rinaldi CA, Niederer SA (2019) Biophys J, 117(12): 2375-2381.
PMID: 31547974, DOI: 10.1016/j.bpj.2019.08.025

Factors Promoting Conduction Slowing as Substrates for Block and Reentry in Infarcted Hearts.
Campos FO, Whitaker J, Neji R, Roujol S, O'Neill M, Plank G, Bishop MJ (2019) Biophys J, 117(12): 2361-2374.
PMID: 31521328, DOI: 10.1016/j.bpj.2019.08.008

Inverse localization of earliest cardiac activation sites from activation maps based on the viscous Eikonal equation.
Kunisch K, Neic A, Plank G, Trautmann P (2019) J Math Biol, 79(6-7): 2033-2068.
PMID: 31473798, DOI: 10.1007/s00285-019-01419-3

Scar shape analysis and simulated electrical instabilities in a non-ischemic dilated cardiomyopathy patient cohort.
Balaban G, Halliday BP, Bai W, Porter B, Malvuccio C, Lamata P, Rinaldi CA, Plank G, Rueckert D, Prasad SK, Bishop MJ (2019) PLoS Comput Biol, 15(10): e1007421.
PMID: 31658247, DOI: 10.1371/journal.pcbi.1007421

A rule-based method for predicting the electrical activation of the heart with cardiac resynchronization therapy from non-invasive clinical data.
Lee AWC, Nguyen UC, Razeghi O, Gould J, Sidhu BS, Sieniewicz B, Behar J, Mafi-Rad M, Plank G, Prinzen FW, Rinaldi CA, Vernooy K, Niederer S (2019) Med Image Anal, 57: 197-213.
PMID: 31326854, DOI: 10.1016/j.media.2019.06.017

Pacing in proximity to scar during cardiac resynchronization therapy increases local dispersion of repolarization and susceptibility to ventricular arrhythmogenesis.
Mendonca Costa C, Neic A, Kerfoot E, Porter B, Sieniewicz B, Gould J, Sidhu B, Chen Z, Plank G, Rinaldi CA, Bishop MJ, Niederer SA (2019) Heart Rhythm, 16(10): 1475-1483.
PMID: 30930329, DOI: 10.1016/j.hrthm.2019.03.027

Generation of a cohort of whole-torso cardiac models for assessing the utility of a novel computed shock vector efficiency metric for ICD optimisation.
Plancke AM, Connolly A, Gemmell PM, Neic A, McSpadden LC, Whitaker J, O'Neill M, Rinaldi CA, Rajani R, Niederer SA, Plank G, Bishop MJ (2019) Comput Biol Med, 112: 103368.
PMID: 31352217, DOI: 10.1016/j.compbiomed.2019.103368

Optimization of the flight technique in ski jumping: The influence of wind.
Jung A, Müller W, Staat M (2019) J Biomech, 88: 190-193.
PMID: 30940358, DOI: 10.1016/j.jbiomech.2019.03.023

The Left and Right Ventricles Respond Differently to Variation of Pacing Delays in Cardiac Resynchronization Therapy: A Combined Experimental- Computational Approach.
Willemen E, Schreurs R, Huntjens PR, Strik M, Plank G, Vigmond E, Walmsley J, Vernooy K, Delhaas T, Prinzen FW, Lumens J (2019) Front Physiol, 10: 17.
PMID: 30774598, DOI: 10.3389/fphys.2019.00017

Validation of Intramural Wavefront Reconstruction and Estimation of 3D Conduction Velocity.
Good WW, Gillette KK, Bergquist JA, Zenger B, Tate J, Rupp LC, Anderson D, Plank G, MacLeod RS (2019) Comput Cardiol (2010), 46PMID: 32123687, DOI: 10.22489/cinc.2019.420

2018

Fibrosis Microstructure Modulates Reentry in Non-ischemic Dilated Cardiomyopathy: Insights From Imaged Guided 2D Computational Modeling.
Balaban G, Halliday BP, Mendonca Costa C, Bai W, Porter B, Rinaldi CA, Plank G, Rueckert D, Prasad SK, Bishop MJ (2018) Front Physiol, 9: 1832.
PMID: 30618838, DOI: 10.3389/fphys.2018.01832

Phosphorylation by the stress-activated MAPK Slt2 down-regulates the yeast TOR complex 2.
Leskoske KL, Roelants FM, Emmerstorfer-Augustin A, Augustin CM, Si EP, Hill JM, Thorner J (2018) Genes Dev, 32(23-24): 1576-1590.
PMID: 30478248, DOI: 10.1101/gad.318709.118

Assessment of wall stresses and mechanical heart power in the left ventricle: Finite element modeling versus Laplace analysis.
Gsell MAF, Augustin CM, Prassl AJ, Karabelas E, Fernandes JF, Kelm M, Goubergrits L, Kuehne T, Plank G (2018) Int J Numer Method Biomed Eng, 34(12): e3147.
PMID: 30151998, DOI: 10.1002/cnm.3147

Tracking yeast pheromone receptor Ste2 endocytosis using fluorogen-activating protein tagging.
Emmerstorfer-Augustin A, Augustin CM, Shams S, Thorner J (2018) Mol Biol Cell, 29(22): 2720-2736.
PMID: 30207829, DOI: 10.1091/mbc.E18-07-0424

Arterial hypertension drives arrhythmia progression via specific structural remodeling in a porcine model of atrial fibrillation.
Manninger M, Zweiker D, van Hunnik A, Alogna A, Prassl AJ, Schipke J, Zeemering S, Zirngast B, Schönleitner P, Schwarzl M, Herbst V, Thon-Gutschi E, Huber S, Rohrer U, Ebner J, Brussee H, Pieske BM, Heinzel FR, Verheule S, Antoons G, Lueger A, Mühlfeld C, Plank G, Schotten U, Post H, Scherr D (2018) Heart Rhythm, 15(9): 1328-1336.
PMID: 29803020, DOI: 10.1016/j.hrthm.2018.05.016

Personalized computational modeling of left atrial geometry and transmural myofiber architecture.
Fastl TE, Tobon-Gomez C, Crozier A, Whitaker J, Rajani R, McCarthy KP, Sanchez-Quintana D, Ho SY, O'Neill MD, Plank G, Bishop MJ, Niederer SA (2018) Med Image Anal, 47: 180-190.
PMID: 29753182, DOI: 10.1016/j.media.2018.04.001

A work flow to build and validate patient specific left atrium electrophysiology models from catheter measurements.
Corrado C, Williams S, Karim R, Plank G, O'Neill M, Niederer S (2018) Med Image Anal, 47: 153-163.
PMID: 29753180, DOI: 10.1016/j.media.2018.04.005

Wind and fairness in ski jumping: A computer modelling analysis.
Jung A, Müller W, Staat M (2018) J Biomech, 75: 147-153.
PMID: 29803308, DOI: 10.1016/j.jbiomech.2018.05.001

Towards a Computational Framework for Modeling the Impact of Aortic Coarctations Upon Left Ventricular Load.
Karabelas E, Gsell MAF, Augustin CM, Marx L, Neic A, Prassl AJ, Goubergrits L, Kuehne T, Plank G (2018) Front Physiol, 9: 538.
PMID: 29892227, DOI: 10.3389/fphys.2018.00538

Corrigendum to "Flight style optimization in ski jumping on normal, large, and ski flying hills" [J. Biomech 47 (2014) 716-722].
Jung A, Staat M, Müller W (2018) J Biomech, 71: 313.
PMID: 29456170, DOI: 10.1016/j.jbiomech.2018.02.001

Modeling the Electrophysiological Properties of the Infarct Border Zone.
Mendonca Costa C, Plank G, Rinaldi CA, Niederer SA, Bishop MJ (2018) Front Physiol, 9: 356.
PMID: 29686626, DOI: 10.3389/fphys.2018.00356

Universal ventricular coordinates: A generic framework for describing position within the heart and transferring data.
Bayer J, Prassl AJ, Pashaei A, Gomez JF, Frontera A, Neic A, Plank G, Vigmond EJ (2018) Med Image Anal, 45: 83-93.
PMID: 29414438, DOI: 10.1016/j.media.2018.01.005

2017

Efficient computation of electrograms and ECGs in human whole heart simulations using a reaction-eikonal model.
Neic A, Campos FO, Prassl AJ, Niederer SA, Bishop MJ, Vigmond EJ, Plank G (2017) J Comput Phys, 346: 191-211.
PMID: 28819329, DOI: 10.1016/j.jcp.2017.06.020

Highly trabeculated structure of the human endocardium underlies asymmetrical response to low-energy monophasic shocks.
Connolly A, Robson MD, Schneider J, Burton R, Plank G, Bishop MJ (2017) Chaos, 27(9): 093913.
PMID: 28964115, DOI: 10.1063/1.4999609

Stochastic spontaneous calcium release events and sodium channelopathies promote ventricular arrhythmias.
Campos FO, Shiferaw Y, Vigmond EJ, Plank G (2017) Chaos, 27(9): 093910.
PMID: 28964108, DOI: 10.1063/1.4999612

Assessment of reduced-order unscented Kalman filter for parameter identification in 1-dimensional blood flow models using experimental data.
Caiazzo A, Caforio F, Montecinos G, Muller LO, Blanco PJ, Toro EF (2017) Int J Numer Method Biomed Eng, 33(8): e2843.
PMID: 27781397, DOI: 10.1002/cnm.2843

Advantages and problems of nonlinear methods applied to analyze physiological time signals: human balance control as an example.
Müller W, Jung A, Ahammer H (2017) Sci Rep, 7(1): 2464.
PMID: 28550294, DOI: 10.1038/s41598-017-02665-5

Biophysical Modeling to Determine the Optimization of Left Ventricular Pacing Site and AV/VV Delays in the Acute and Chronic Phase of Cardiac Resynchronization Therapy.
Lee AW, Crozier A, Hyde ER, Lamata P, Truong M, Sohal M, Jackson T, Behar JM, Claridge S, Shetty A, Sammut E, Plank G, Rinaldi CA, Niederer S (2017) J Cardiovasc Electrophysiol, 28(2): 208-215.
PMID: 27885749, DOI: 10.1111/jce.13134

2016

Patient-specific modeling of left ventricular electromechanics as a driver for haemodynamic analysis.
Augustin CM, Crozier A, Neic A, Prassl AJ, Karabelas E, Ferreira da Silva T, Fernandes JF, Campos F, Kuehne T, Plank G (2016) Europace, 18(suppl 4): iv121-iv129.
PMID: 28011839, DOI: 10.1093/europace/euw369

Analysis of lead placement optimization metrics in cardiac resynchronization therapy with computational modelling.
Crozier A, Blazevic B, Lamata P, Plank G, Ginks M, Duckett S, Sohal M, Shetty A, Rinaldi CA, Razavi R, Niederer SA, Smith NP (2016) Europace, 18(suppl 4): iv113-iv120.
PMID: 28011838, DOI: 10.1093/europace/euw366

Track Z. Training and Further Education for Engineers and Physicians.
Hofer E, Arnold R, Reishofer G, Ahammer H (2016) Biomed Tech (Berl), 61(s1): 262-266.
PMID: 27682706, DOI: 10.1515/bmt-2016-5024

Automated Texture Analysis and Determination of Fibre Orientation of Heart Tissue: A Morphometric Study.
Zach B, Hofer E, Asslaber M, Ahammer H (2016) PLoS One, 11(8): e0160735.
PMID: 27505420, DOI: 10.1371/journal.pone.0160735

The relative role of patient physiology and device optimisation in cardiac resynchronisation therapy: A computational modelling study.
Crozier A, Blazevic B, Lamata P, Plank G, Ginks M, Duckett S, Sohal M, Shetty A, Rinaldi CA, Razavi R, Smith NP, Niederer SA (2016) J Mol Cell Cardiol, 96: 93-100.
PMID: 26546827, DOI: 10.1016/j.yjmcc.2015.10.026

PDE constrained optimization of electrical defibrillation in a 3D ventricular slice geometry.
Chamakuri N, Kunisch K, Plank G (2016) Int J Numer Method Biomed Eng, 32(4): e02742.
PMID: 26249168, DOI: 10.1002/cnm.2742

Investigating a Novel Activation-Repolarisation Time Metric to Predict Localised Vulnerability to Reentry Using Computational Modelling.
Hill YR, Child N, Hanson B, Wallman M, Coronel R, Plank G, Rinaldi CA, Gill J, Smith NP, Taggart P, Bishop MJ (2016) PLoS One, 11(3): e0149342.
PMID: 26934736, DOI: 10.1371/journal.pone.0149342

Three-dimensional atrial wall thickness maps to inform catheter ablation procedures for atrial fibrillation.
Bishop M, Rajani R, Plank G, Gaddum N, Carr-White G, Wright M, O'Neill M, Niederer S (2016) Europace, 18(3): 376-83.
PMID: 25842272, DOI: 10.1093/europace/euv073

Anatomically accurate high resolution modeling of human whole heart electromechanics: A strongly scalable algebraic multigrid solver method for nonlinear deformation.
Augustin CM, Neic A, Liebmann M, Prassl AJ, Niederer SA, Haase G, Plank G (2016) J Comput Phys, 305: 622-646.
PMID: 26819483, DOI: 10.1016/j.jcp.2015.10.045

Image-Based Personalization of Cardiac Anatomy for Coupled Electromechanical Modeling.
Crozier A, Augustin CM, Neic A, Prassl AJ, Holler M, Fastl TE, Hennemuth A, Bredies K, Kuehne T, Bishop MJ, Niederer SA, Plank G (2016) Ann Biomed Eng, 44(1): 58-70.
PMID: 26424476, DOI: 10.1007/s10439-015-1474-5

2015

Verification of cardiac mechanics software: benchmark problems and solutions for testing active and passive material behaviour.
Land S, Gurev V, Arens S, Augustin CM, Baron L, Blake R, Bradley C, Castro S, Crozier A, Favino M, Fastl TE, Fritz T, Gao H, Gizzi A, Griffith BE, Hurtado DE, Krause R, Luo X, Nash MP, Pezzuto S, Plank G, Rossi S, Ruprecht D, Seemann G, Smith NP, Sundnes J, Rice JJ, Trayanova N, Wang D, Jenny Wang Z, Niederer SA (2015) Proc Math Phys Eng Sci, 471(2184): 20150641.
PMID: 26807042, DOI: 10.1098/rspa.2015.0641

Beneficial Effect on Cardiac Resynchronization From Left Ventricular Endocardial Pacing Is Mediated by Early Access to High Conduction Velocity Tissue: Electrophysiological Simulation Study.
Hyde ER, Behar JM, Claridge S, Jackson T, Lee AW, Remme EW, Sohal M, Plank G, Razavi R, Rinaldi CA, Niederer SA (2015) Circ Arrhythm Electrophysiol, 8(5): 1164-72.
PMID: 26136400, DOI: 10.1161/CIRCEP.115.002677

Local Gradients in Electrotonic Loading Modulate the Local Effective Refractory Period: Implications for Arrhythmogenesis in the Infarct Border Zone.
Connolly A, Trew ML, Smaill BH, Plank G, Bishop MJ (2015) IEEE Trans Biomed Eng, 62(9): 2251-2259.
PMID: 25872206, DOI: 10.1109/TBME.2015.2421296

Stochastic spontaneous calcium release events trigger premature ventricular complexes by overcoming electrotonic load.
Campos FO, Shiferaw Y, Prassl AJ, Boyle PM, Vigmond EJ, Plank G (2015) Cardiovasc Res, 107(1): 175-83.
PMID: 25969391, DOI: 10.1093/cvr/cvv149

Biophotonic Modelling of Cardiac Optical Imaging.
Bishop MJ, Plank G (2015) Adv Exp Med Biol, 859: 367-404.
PMID: 26238061, DOI: 10.1007/978-3-319-17641-3_15

2014

Structural heterogeneity modulates effective refractory period: a mechanism of focal arrhythmia initiation.
Bishop MJ, Connolly A, Plank G (2014) PLoS One, 9(10): e109754.
PMID: 25291380, DOI: 10.1371/journal.pone.0109754

Simulating photon scattering effects in structurally detailed ventricular models using a Monte Carlo approach.
Bishop MJ, Plank G (2014) Front Physiol, 5: 338.
PMID: 25309442, DOI: 10.3389/fphys.2014.00338

Influence of the Purkinje-muscle junction on transmural repolarization heterogeneity.
Walton RD, Martinez ME, Bishop MJ, Hocini M, Haïssaguerre M, Plank G, Bernus O, Vigmond EJ (2014) Cardiovasc Res, 103(4): 629-40.
PMID: 24997066, DOI: 10.1093/cvr/cvu165

Classical and all-floating FETI methods for the simulation of arterial tissues.
Augustin CM, Holzapfel GA, Steinbach O (2014) Int J Numer Methods Eng, 99(4): 290-312.
PMID: 26751957, DOI: 10.1002/nme.4674

Sensitivity and specificity of substrate mapping: an in silico framework for the evaluation of electroanatomical substrate mapping strategies.
Blauer JJ, Swenson D, Higuchi K, Plank G, Ranjan R, Marrouche N, Macleod RS (2014) J Cardiovasc Electrophysiol, 25(7): 774-80.
PMID: 24762029, DOI: 10.1111/jce.12444

Mechanism of reentry induction by a 9-V battery in rabbit ventricles.
Bishop MJ, Burton RA, Kalla M, Nanthakumar K, Plank G, Bub G, Vigmond EJ (2014) Am J Physiol Heart Circ Physiol, 306(7): H1041-53.
PMID: 24464758, DOI: 10.1152/ajpheart.00591.2013

An efficient finite element approach for modeling fibrotic clefts in the heart.
Costa CM, Campos FO, Prassl AJ, dos Santos RW, Sánchez-Quintana D, Ahammer H, Hofer E, Plank G (2014) IEEE Trans Biomed Eng, 61(3): 900-10.
PMID: 24557691, DOI: 10.1109/TBME.2013.2292320

Flight style optimization in ski jumping on normal, large, and ski flying hills.
Jung A, Staat M, Müller W (2014) J Biomech, 47(3): 716-22.
PMID: 24388531, DOI: 10.1016/j.jbiomech.2013.11.021

Effects of regional mitochondrial depolarization on electrical propagation: implications for arrhythmogenesis.
Zhou L, Solhjoo S, Millare B, Plank G, Abraham MR, Cortassa S, Trayanova N, O'Rourke B (2014) Circ Arrhythm Electrophysiol, 7(1): 143-51.
PMID: 24382411, DOI: 10.1161/CIRCEP.113.000600

2013

Modeling the dispersion in electromechanically coupled myocardium.
Eriksson TS, Prassl AJ, Plank G, Holzapfel GA (2013) Int J Numer Method Biomed Eng, 29(11): 1267-84.
PMID: 23868817, DOI: 10.1002/cnm.2575

Automatic Parameterization Strategy for Cardiac Electrophysiology Simulations.
Costa CM, Hoetzl E, Rocha BM, Prassl AJ, Plank G (2013) Comput Cardiol (2010), 40: 373-376.
PMID: 24729986

On boundary stimulation and optimal boundary control of the bidomain equations.
Chamakuri N, Kunisch K, Plank G (2013) Math Biosci, 245(2): 206-15.
PMID: 23856647, DOI: 10.1016/j.mbs.2013.07.004

Simulating the Mechanics of Myocardial Tissue Using Strongly Scalable Parallel Algorithms.
Augustin CM, Plank G (2013) Biomed Tech (Berl), 58 Suppl 1(Suppl 1)PMID: 24043067, DOI: 10.1515/bmt-2013-4322

Tissue Structure and Ca2+-Mediated Ectopic Beats.
Campos FO, Shiferaw Y, Plank G (2013) Biomed Tech (Berl), 58 Suppl 1(Suppl 1)PMID: 24043060, DOI: 10.1515/bmt-2013-4320

Computational Challenges in Building Multi-Scale and Multi-Physics Models of Cardiac Electro-Mechanics.
Plank G, Prassl AJ, Augustin C (2013) Biomed Tech (Berl), 58 Suppl 1(Suppl 1)PMID: 24043050, DOI: 10.1515/bmt-2013-4318

Electroanatomical characterization of atrial microfibrosis in a histologically detailed computer model.
Campos FO, Wiener T, Prassl AJ, dos Santos RW, Sanchez-Quintana D, Ahammer H, Plank G, Hofer E (2013) IEEE Trans Biomed Eng, 60(8): 2339-49.
PMID: 23559023, DOI: 10.1109/TBME.2013.2256359

Optimal control approach to termination of re-entry waves in cardiac electrophysiology.
Nagaiah C, Kunisch K, Plank G (2013) J Math Biol, 67(2): 359-88.
PMID: 22684847, DOI: 10.1007/s00285-012-0557-2

Tachycardia in post-infarction hearts: insights from 3D image-based ventricular models.
Arevalo H, Plank G, Helm P, Halperin H, Trayanova N (2013) PLoS One, 8(7): e68872.
PMID: 23844245, DOI: 10.1371/journal.pone.0068872

Mechanistic inquiry into the role of tissue remodeling in fibrotic lesions in human atrial fibrillation.
McDowell KS, Vadakkumpadan F, Blake R, Blauer J, Plank G, Macleod RS, Trayanova NA (2013) Biophys J, 104(12): 2764-73.
PMID: 23790385, DOI: 10.1016/j.bpj.2013.05.025

The functional role of electrophysiological heterogeneity in the rabbit ventricle during rapid pacing and arrhythmias.
Bishop MJ, Vigmond EJ, Plank G (2013) Am J Physiol Heart Circ Physiol, 304(9): H1240-52.
PMID: 23436328, DOI: 10.1152/ajpheart.00894.2012

FETI Methods for the Simulation of Biological Tissues.
Augustin C, Steinbach O (2013) Domain Decompos Method Sci Eng XX (2011), 91: 503-510.
PMID: 26925469, DOI: 10.1007/978-3-642-35275-1_59

2012

Methodology for patient-specific modeling of atrial fibrosis as a substrate for atrial fibrillation.
McDowell KS, Vadakkumpadan F, Blake R, Blauer J, Plank G, MacLeod RS, Trayanova NA (2012) J Electrocardiol, 45(6): 640-5.
PMID: 22999492, DOI: 10.1016/j.jelectrocard.2012.08.005

Decomposition of fractionated local electrograms using an analytic signal model based on sigmoid functions.
Wiener T, Campos FO, Plank G, Hofer E (2012) Biomed Tech (Berl), 57(5): 371-82.
PMID: 23027582, DOI: 10.1515/bmt-2012-0008

Spongious hypertrophic cardiomyopathy in patients with mutations in the four-and-a-half LIM domain 1 gene.
Binder JS, Weidemann F, Schoser B, Niemann M, Machann W, Beer M, Plank G, Schmidt A, Bisping E, Poparic I, Lafer I, Stojakovic T, Quasthoff S, Vincent JB, Rienmueller R, Speicher MR, Berghold A, Pieske B, Windpassinger C (2012) Circ Cardiovasc Genet, 5(5): 490-502.
PMID: 22923418, DOI: 10.1161/CIRCGENETICS.111.962332

A novel rule-based algorithm for assigning myocardial fiber orientation to computational heart models.
Bayer JD, Blake RC, Plank G, Trayanova NA (2012) Ann Biomed Eng, 40(10): 2243-54.
PMID: 22648575, DOI: 10.1007/s10439-012-0593-5

The role of fine-scale anatomical structure in the dynamics of reentry in computational models of the rabbit ventricles.
Bishop MJ, Plank G (2012) J Physiol, 590(18): 4515-35.
PMID: 22753546, DOI: 10.1113/jphysiol.2012.229062

Three-dimensional mechanisms of increased vulnerability to electric shocks in myocardial infarction: altered virtual electrode polarizations and conduction delay in the peri-infarct zone.
Rantner LJ, Arevalo HJ, Constantino JL, Efimov IR, Plank G, Trayanova NA (2012) J Physiol, 590(18): 4537-51.
PMID: 22586222, DOI: 10.1113/jphysiol.2012.229088

Accelerating cardiac bidomain simulations using graphics processing units.
Neic A, Liebmann M, Hoetzl E, Mitchell L, Vigmond EJ, Haase G, Plank G (2012) IEEE Trans Biomed Eng, 59(8): 2281-90.
PMID: 22692867, DOI: 10.1109/TBME.2012.2202661

Influence of ischemic core muscle fibers on surface depolarization potentials in superfused cardiac tissue preparations: a simulation study.
Campos FO, Prassl AJ, Seemann G, Weber dos Santos R, Plank G, Hofer E (2012) Med Biol Eng Comput, 50(5): 461-72.
PMID: 22411321, DOI: 10.1007/s11517-012-0880-1

Investigating the role of the coronary vasculature in the mechanisms of defibrillation.
Bishop MJ, Plank G, Vigmond E (2012) Circ Arrhythm Electrophysiol, 5(1): 210-9.
PMID: 22157522, DOI: 10.1161/CIRCEP.111.965095

Biophysical modeling to simulate the response to multisite left ventricular stimulation using a quadripolar pacing lead.
Niederer SA, Shetty AK, Plank G, Bostock J, Razavi R, Smith NP, Rinaldi CA (2012) Pacing Clin Electrophysiol, 35(2): 204-14.
PMID: 22040178, DOI: 10.1111/j.1540-8159.2011.03243.x

Analyses of the redistribution of work following cardiac resynchronisation therapy in a patient specific model.
Niederer SA, Lamata P, Plank G, Chinchapatnam P, Ginks M, Rhode K, Rinaldi CA, Razavi R, Smith NP (2012) PLoS One, 7(8): e43504.
PMID: 22952697, DOI: 10.1371/journal.pone.0043504

2011

Cardiac bidomain bath-loading effects during arrhythmias: interaction with anatomical heterogeneity.
Bishop MJ, Vigmond E, Plank G (2011) Biophys J, 101(12): 2871-81.
PMID: 22208185, DOI: 10.1016/j.bpj.2011.10.052

Verification of cardiac tissue electrophysiology simulators using an N-version benchmark.
Niederer SA, Kerfoot E, Benson AP, Bernabeu MO, Bernus O, Bradley C, Cherry EM, Clayton R, Fenton FH, Garny A, Heidenreich E, Land S, Maleckar M, Pathmanathan P, Plank G, Rodríguez JF, Roy I, Sachse FB, Seemann G, Skavhaug O, Smith NP (2011) Philos Trans A Math Phys Eng Sci, 369(1954): 4331-51.
PMID: 21969679, DOI: 10.1098/rsta.2011.0139

Inter-model consistency and complementarity: learning from ex-vivo imaging and electrophysiological data towards an integrated understanding of cardiac physiology.
Camara O, Sermesant M, Lamata P, Wang L, Pop M, Relan J, De Craene M, Delingette H, Liu H, Niederer S, Pashaei A, Plank G, Romero D, Sebastian R, Wong KC, Zhang H, Ayache N, Frangi AF, Shi P, Smith NP, Wright GA (2011) Prog Biophys Mol Biol, 107(1): 122-33.
PMID: 21791225, DOI: 10.1016/j.pbiomolbio.2011.07.007

Bidomain ECG simulations using an augmented monodomain model for the cardiac source.
Bishop MJ, Plank G (2011) IEEE Trans Biomed Eng, 58(8)PMID: 21536529, DOI: 10.1109/TBME.2011.2148718

The role of photon scattering in voltage-calcium fluorescent recordings of ventricular fibrillation.
Bishop MJ, Rowley A, Rodriguez B, Plank G, Gavaghan DJ, Bub G (2011) Biophys J, 101(2): 307-18.
PMID: 21767482, DOI: 10.1016/j.bpj.2011.06.012

Estimation of local orientations in fibrous structures with applications to the Purkinje system.
Cetingül HE, Plank G, Trayanova NA, Vidal R (2011) IEEE Trans Biomed Eng, 58(6): 1762-72.
PMID: 21335301, DOI: 10.1109/TBME.2011.2116119

Simulating human cardiac electrophysiology on clinical time-scales.
Niederer S, Mitchell L, Smith N, Plank G (2011) Front Physiol, 2: 14.
PMID: 21516246, DOI: 10.3389/fphys.2011.00014

Representing cardiac bidomain bath-loading effects by an augmented monodomain approach: application to complex ventricular models.
Bishop MJ, Plank G (2011) IEEE Trans Biomed Eng, 58(4): 1066-75.
PMID: 21292591, DOI: 10.1109/TBME.2010.2096425

A macro finite-element formulation for cardiac electrophysiology simulations using hybrid unstructured grids.
Rocha BM, Kickinger F, Prassl AJ, Haase G, Vigmond EJ, dos Santos RW, Zaglmayr S, Plank G (2011) IEEE Trans Biomed Eng, 58(4): 1055-65.
PMID: 20699206, DOI: 10.1109/TBME.2010.2064167

Length-dependent tension in the failing heart and the efficacy of cardiac resynchronization therapy.
Niederer SA, Plank G, Chinchapatnam P, Ginks M, Lamata P, Rhode KS, Rinaldi CA, Razavi R, Smith NP (2011) Cardiovasc Res, 89(2): 336-43.
PMID: 20952413, DOI: 10.1093/cvr/cvq318

Modeling defibrillation of the heart: approaches and insights.
Trayanova N, Constantino J, Ashihara T, Plank G (2011) IEEE Rev Biomed Eng, 4: 89-102.
PMID: 22273793, DOI: 10.1109/RBME.2011.2173761

A finite element approach for modeling micro-structural discontinuities in the heart.
Costa CM, Campos FO, Prassl AJ, dos Santos RW, Sánchez-Quintana D, Hofer E, Plank G (2011) Annu Int Conf IEEE Eng Med Biol Soc, 2011: 437-40.
PMID: 22254342, DOI: 10.1109/IEMBS.2011.6090059

2010

Modeling the role of the coronary vasculature during external field stimulation.
Bishop MJ, Boyle PM, Plank G, Welsh DG, Vigmond EJ (2010) IEEE Trans Biomed Eng, 57(10): 2335-45.
PMID: 20542762, DOI: 10.1109/TBME.2010.2051227

Image-based models of cardiac structure in health and disease.
Vadakkumpadan F, Arevalo H, Prassl AJ, Chen J, Kickinger F, Kohl P, Plank G, Trayanova N (2010) Wiley Interdiscip Rev Syst Biol Med, 2(4): 489-506.
PMID: 20582162, DOI: 10.1002/wsbm.76

Development of an anatomically detailed MRI-derived rabbit ventricular model and assessment of its impact on simulations of electrophysiological function.
Bishop MJ, Plank G, Burton RA, Schneider JE, Gavaghan DJ, Grau V, Kohl P (2010) Am J Physiol Heart Circ Physiol, 298(2): H699-718.
PMID: 19933417, DOI: 10.1152/ajpheart.00606.2009

Purkinje-mediated effects in the response of quiescent ventricles to defibrillation shocks.
Boyle PM, Deo M, Plank G, Vigmond EJ (2010) Ann Biomed Eng, 38(2): 456-68.
PMID: 19876737, DOI: 10.1007/s10439-009-9829-4

A 2D-computer model of atrial tissue based on histographs describes the electro-anatomical impact of microstructure on endocardiac potentials and electric near-fields.
Campos FO, Wiener T, Prassl AJ, Ahammer H, Plank G, Weber Dos Santos R, Sánchez-Quintana D, Hofer E (2010) Annu Int Conf IEEE Eng Med Biol Soc, 2010: 2541-4.
PMID: 21096441, DOI: 10.1109/IEMBS.2010.5626870

2009

Arrhythmogenic mechanisms of the Purkinje system during electric shocks: a modeling study.
Deo M, Boyle P, Plank G, Vigmond E (2009) Heart Rhythm, 6(12): 1782-9.
PMID: 19959130, DOI: 10.1016/j.hrthm.2009.08.023

Solving the coupled system improves computational efficiency of the bidomain equations.
Southern JA, Plank G, Vigmond EJ, Whiteley JP (2009) IEEE Trans Biomed Eng, 56(10): 2404-12.
PMID: 19457741, DOI: 10.1109/TBME.2009.2022548

Generation of histo-anatomically representative models of the individual heart: tools and application.
Plank G, Burton RA, Hales P, Bishop M, Mansoori T, Bernabeu MO, Garny A, Prassl AJ, Bollensdorff C, Mason F, Mahmood F, Rodriguez B, Grau V, Schneider JE, Gavaghan D, Kohl P (2009) Philos Trans A Math Phys Eng Sci, 367(1896): 2257-92.
PMID: 19414455, DOI: 10.1098/rsta.2009.0056

Towards predictive modelling of the electrophysiology of the heart.
Vigmond E, Vadakkumpadan F, Gurev V, Arevalo H, Deo M, Plank G, Trayanova N (2009) Exp Physiol, 94(5): 563-77.
PMID: 19270037, DOI: 10.1113/expphysiol.2008.044073

Automatically generated, anatomically accurate meshes for cardiac electrophysiology problems.
Prassl AJ, Kickinger F, Ahammer H, Grau V, Schneider JE, Hofer E, Vigmond EJ, Trayanova NA, Plank G (2009) IEEE Trans Biomed Eng, 56(5): 1318-30.
PMID: 19203877, DOI: 10.1109/TBME.2009.2014243

Image-based models of cardiac structure with applications in arrhythmia and defibrillation studies.
Vadakkumpadan F, Rantner LJ, Tice B, Boyle P, Prassl AJ, Vigmond E, Plank G, Trayanova N (2009) J Electrocardiol, 42(2): 157.e1-10.
PMID: 19181330, DOI: 10.1016/j.jelectrocard.2008.12.003

Low energy defibrillation in human cardiac tissue: a simulation study.
Morgan SW, Plank G, Biktasheva IV, Biktashev VN (2009) Biophys J, 96(4): 1364-73.
PMID: 19217854, DOI: 10.1016/j.bpj.2008.11.031

Near-real-time simulations of biolelectric activity in small mammalian hearts using graphical processing units.
Vigmond EJ, Boyle PM, Leon L, Plank G (2009) Annu Int Conf IEEE Eng Med Biol Soc, 2009: 3290-3.
PMID: 19964295, DOI: 10.1109/IEMBS.2009.5333738

2008

From mitochondrial ion channels to arrhythmias in the heart: computational techniques to bridge the spatio-temporal scales.
Plank G, Zhou L, Greenstein JL, Cortassa S, Winslow RL, O'Rourke B, Trayanova NA (2008) Philos Trans A Math Phys Eng Sci, 366(1879): 3381-409.
PMID: 18603526, DOI: 10.1098/rsta.2008.0112

Evaluating intramural virtual electrodes in the myocardial wedge preparation: simulations of experimental conditions.
Plank G, Prassl A, Hofer E, Trayanova NA (2008) Biophys J, 94(5): 1904-15.
PMID: 17993491, DOI: 10.1529/biophysj.107.121343

Role of Purkinje system in cardiac arrhythmias.
Deo M, Boyle P, Plank G, Vigmond E (2008) Annu Int Conf IEEE Eng Med Biol Soc, 2008: 149-52.
PMID: 19162615, DOI: 10.1109/IEMBS.2008.4649112

A finite element formulation for atrial tissue monolayer.
Wieser L, Richter HE, Plank G, Pfeifer B, Tilg B, Nowak CN, Fischer G (2008) Methods Inf Med, 47(2): 131-9.
PMID: 18338084, DOI: 10.3414/me0414

Solvers for the cardiac bidomain equations.
Vigmond EJ, Weber dos Santos R, Prassl AJ, Deo M, Plank G (2008) Prog Biophys Mol Biol, 96(1-3): 3-18.
PMID: 17900668, DOI: 10.1016/j.pbiomolbio.2007.07.012

2007

Reduced-order preconditioning for bidomain simulations.
Deo M, Bauer S, Plank G, Vigmond E (2007) IEEE Trans Biomed Eng, 54(5): 938-42.
PMID: 17518292, DOI: 10.1109/TBME.2006.889203

Algebraic multigrid preconditioner for the cardiac bidomain model.
Plank G, Liebmann M, Weber dos Santos R, Vigmond EJ, Haase G (2007) IEEE Trans Biomed Eng, 54(4): 585-96.
PMID: 17405366, DOI: 10.1109/TBME.2006.889181

Oblique propagation of activation allows the detection of uncoupling microstructures from cardiac near field behavior.
Hofer E, Wiener T, Prassl AJ, Thurner T, Plank G (2007) Annu Int Conf IEEE Eng Med Biol Soc, 2007: 415-8.
PMID: 18001978, DOI: 10.1109/IEMBS.2007.4352312

Arrhythmogenesis research: a perspective from computational electrophysiology viewpoint.
Trayanova N, Plank G (2007) Annu Int Conf IEEE Eng Med Biol Soc, 2007: 406-9.
PMID: 18001976, DOI: 10.1109/IEMBS.2007.4352310

Accuracy of local conduction velocity determination from non-fractionated cardiac activation signals.
Wiener T, Thurner T, Prassl AJ, Plank G, Hofer E (2007) Annu Int Conf IEEE Eng Med Biol Soc, 2007: 27-30.
PMID: 18001880, DOI: 10.1109/IEMBS.2007.4352214

2006

Three-dimensional models of individual cardiac histoanatomy: tools and challenges.
Burton RA, Plank G, Schneider JE, Grau V, Ahammer H, Keeling SL, Lee J, Smith NP, Gavaghan D, Trayanova N, Kohl P (2006) Ann N Y Acad Sci, 1080: 301-19.
PMID: 17132791, DOI: 10.1196/annals.1380.023

What have we learned from mathematical models of defibrillation and postshock arrhythmogenesis? Application of bidomain simulations.
Trayanova N, Plank G, Rodríguez B (2006) Heart Rhythm, 3(10): 1232-5.
PMID: 17018358, DOI: 10.1016/j.hrthm.2006.04.015

A new floating sensor array to detect electric near fields of beating heart preparations.
Hofer E, Keplinger F, Thurner T, Wiener T, Sanchez-Quintana D, Climent V, Plank G (2006) Biosens Bioelectron, 21(12): 2232-9.
PMID: 16384696, DOI: 10.1016/j.bios.2005.11.010

Accelerating large cardiac bidomain simulations by arnoldi preconditioning.
Deo M, Bauer S, Plank G, Vigmond E (2006) Conf Proc IEEE Eng Med Biol Soc, 2006: 3923-6.
PMID: 17946209, DOI: 10.1109/IEMBS.2006.259271

2005

Contributions of Purkinje-myocardial coupling to suppression and facilitation of early afterdepolarization-induced triggered activity.
Schafferhofer-Steltzer I, Hofer E, Huelsing DJ, Bishop SP, Pollard AE (2005) IEEE Trans Biomed Eng, 52(9): 1522-31.
PMID: 16189965, DOI: 10.1109/TBME.2005.851528

Defibrillation depends on conductivity fluctuations and the degree of disorganization in reentry patterns.
Plank G, Leon LJ, Kimber S, Vigmond EJ (2005) J Cardiovasc Electrophysiol, 16(2): 205-16.
PMID: 15720461, DOI: 10.1046/j.1540-8167.2005.40140.x

2004

Parallel multigrid preconditioner for the cardiac bidomain model.
Weber dos Santos R, Plank G, Bauer S, Vigmond EJ (2004) IEEE Trans Biomed Eng, 51(11): 1960-8.
PMID: 15536898, DOI: 10.1109/TBME.2004.834275

2003

Cardiac near-field morphology during conduction around a microscopic obstacle--a computer simulation study.
Plank G, Vigmond E, Leon LJ, Hofer E (2003) Ann Biomed Eng, 31(10): 1206-12.
PMID: 14649494, DOI: 10.1114/1.1615573

Use of cardiac electric near-field measurements to determine activation times.
Plank G, Hofer E (2003) Ann Biomed Eng, 31(9): 1066-76.
PMID: 14582609, DOI: 10.1114/1.1603258

Computational tools for modeling electrical activity in cardiac tissue.
Vigmond EJ, Hughes M, Plank G, Leon LJ (2003) J Electrocardiol, 36 Suppl: 69-74.
PMID: 14716595, DOI: 10.1016/j.jelectrocard.2003.09.017

2000

Model study of vector-loop morphology during electrical mapping of microscopic conduction in cardiac tissue.
Plank G, Hofer E (2000) Ann Biomed Eng, 28(10): 1244-52.
PMID: 11144985, DOI: 10.1114/1.1320841

1999

A new real-time mapping system to detect microscopic cardiac excitation patterns.
Mohr G, Hofer E, Plank G (1999) Biomed Instrum Technol, 33(5): 455-61.
PMID: 10511916

Comparison between the role of discontinuities in cardiac conduction and in a one-dimensional hardware model.
deCastro M, Hofer E, Muñuzuri AP, Gómez-Gesteira M, Plank G, Schafferhofer I, Pérez-Muñuzuri V, Pérez-Villar V (1999) Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics, 59(5 Pt B): 5962-9.
PMID: 11969578, DOI: 10.1103/physreve.59.5962